Program
In each session, speakers from an experimental and theoretical background present their individual perspectives to provide a combined view of the covered topics.
Time |
Sun, 2 Feb |
Mon, 3 Feb |
Tue, 4 Feb |
Wed, 5 Feb |
Thu, 6 Feb |
| 08:00 | Breakfast | Breakfast | Breakfast | Breakfast | |
| 09:00 | I: Energy Landscapes | III: Protein Folding, Evolution & Design | IV: Forces in Folding |
Continuation of V VI: Dynamics of Proteins with Complex Structures |
|
| 12:30 | Lunch | Lunch | Lunch | Lunch | |
| 14:00 | 16:00: Registration | II: Physics of Folding | Excursion to Drachenfels & Dinner | V: Large Biomolecular Assemblies |
Continuation of VI 16:15: Concluding Remarks and Poster Award |
| 18:00 | Dinner | Dinner | Dinner | ||
| 19:30 | 19:00: Introductionary Talks | Poster Session (even) | Poster Session (odd) |
Sun, 2 Feb 2014
|
16:00 – 21:00 |
Registration |
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|
17:30 |
DINNER |
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Introductory Talks - Chair: Alexander Schug |
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|
19:00 |
José Onuchic |
Exploring the energy landscape for protein folding to biomolecular machines of life |
|
19:50 |
Sheena Radford |
The challenges and opportunities of understanding protein folding and protein misfolding in health and disease |
Mon, 3 Feb 2014
|
08:00 |
BREAKFAST |
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|
09:00 – 09:20 |
Ernst Dreisigacker |
About the Wilhelm and Else Heraeus Foundation |
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I. Energy Landscapes - Chair: Paul Whitford |
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|
09:20 – 10:05 |
Victor Muñoz |
Catching protein folding transition paths over a vanishing free energy barrier |
|
10:05 – 10:50 |
Mikael Oliveberg |
Pathologic aggregation in ALS mice follows test-tube behaviour |
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10:50 – 11:20 |
COFFEE BREAK |
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|
11:20 – 12:05 |
Ben Schuler |
Probing the structure and dynamics of unfolded and intrinsically disordered proteins with single-molecule spectroscopy |
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12:05 – 12:50 |
Edward Lemke |
Decoding molecular plasticity underlying nucleocytoplasmic transport |
|
12:50 |
Conference Photo (in the front of the Physikzentrum) |
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|
13:00 |
LUNCH |
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II. Physics of Folding - Chair: Shachi Gosavi |
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|
14:30 – 15:15 |
Gerd Ulrich Nienhaus |
Single-molecule fluorescence studies of Diels-Alderase ribozyme folding and function |
|
15:15 – 16:00 |
William Eaton |
Toward observing transition paths in protein folding by single molecule fluorescence |
|
16:00 – 16:30 |
COFFEE BREAK |
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|
16:30 – 17:15 |
Gerhard Hummer |
Do nonnative interactions matter in protein folding? |
|
17:15 – 18:00 |
Pernilla |
Effects of macromolecular crowding agents on protein folding landscapes in vitro |
|
18:00 – 18:45 |
Wolfgang Wenzel |
Thermodynamic characterization of protein folding equilibriums at the all atom level |
|
19:00 |
DINNER |
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|
19:45 |
Poster session (even) & informal discussion |
|
Tue, 4 Feb 2014
|
08:00 |
BREAKFAST |
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|
III. Protein Folding, Evolution & Design - Chair: Joanna Sulkowska |
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|
09:00 – 09:45 |
Hendrik Szurmant |
Bacterial signal transduction mechanisms and functions |
|
09:45 – 10:30 |
Martin Weigt |
From residue coevolution to protein (complex) structure prediction |
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10:30 – 11:00 |
COFFEE BREAK |
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|
11:00 – 11:45 |
David Wales |
Energy landscapes for biomolecular folding and assembly |
|
11:45 – 12:30 |
Shachi Gosavi |
Building and understanding protein scaffolds |
|
12:30 |
LUNCH |
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|
14:00 |
Excursion |
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|
18:00 |
HERAEUS DINNER (cold & warm buffet, free beverages) |
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Wed, 5 Feb 2014
|
08:00 |
BREAKFAST |
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|
III. Protein Folding, Evolution & Design - Chair: Joanna Sulkowska |
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|
09:00 – 09:45 |
Helmut Grubmüller |
Atomistic simulation of single molecule experiments: Molecular machines and a dynasome perspective ABSTRACT FEHLT |
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IV. Forces in Folding - Chair: Hendrik Szurmant |
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|
09:45 – 10:30 |
Matthias Rief |
Single molecule mechanics of proteins |
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10:30 – 11:00 |
COFFEE BREAK |
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|
11:00 – 11:45 |
Frauke Gräter |
Unfolded and disordered proteins at work - dynamics of collapse and association |
|
11:45 – 12:30 |
Hendrik Dietz |
Sequence, shape, function: exploring biomolecular folding with DNA |
|
12:30 |
LUNCH |
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|
14:00 – 14:45 |
Joanna Sulkowska |
Knotting a protein in explicit solvent |
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V. Large Assemblies - Chair: Frauke Gräter |
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|
14:45 – 15:30 |
Orsolya Barabas |
Juggling with DNA: Mechanisms of assembly and function in DNA transposition. |
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15:30 – 16:15 |
Paul Whitford |
Exploring the energy landscape of ribosome function through simulation |
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16:15 – 16:45 |
COFFEE BREAK |
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16:45 – 17:30 |
Changbong Hyeon |
Mapping allosteric signaling pathways of G-protein coupled receptors |
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17:30 – 18:15 |
Robert Best |
Molecular origins of “internal friction” effects on protein folding rates |
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18:30 |
DINNER |
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|
19:30 |
Poster session (odd) & informal discussion |
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Thu, 6 Feb 2014
|
08:00 |
BREAKFAST |
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|
V. Large Assemblies - Chair: Changbong Hyeon |
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|
09:00 – 09:45 |
Volkhard Helms |
Biomolecular association on funneled energy landscapes |
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09:45 – 10:30 |
Anne Ulrich |
Transport machineries in biomembranes utilizing electrostatic charge zippers |
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10:30 – 11:00 |
COFFEE BREAK |
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|
11:00 – 11:45 |
Birgit Strodel |
Thermodynamics and kinetics for the formation of amyloid oligomers |
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VI. Dynamics of proteins with complex structures - Chair: Orsolya Barabas |
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|
11:45 – 12:30 |
Claus Seidel |
Watching conformational landscapes and invisible states in proteins by high-precision FRET |
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12:30 |
LUNCH |
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|
14:00 – 14:45 |
Magnus Wolf-Watz |
Enzymatic Kcat vs KM compensation interconnected with a conformational pre-equilibrium |
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14:45 – 15:30 |
Ralf Biehl |
Dynamics of proteins with different topology |
|
15:30 – 16:15 |
Alexander Schug |
Co-transcriptional riboswitch folding |
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16:15 – 16:25 |
Abhinav Verma |
Concluding remarks & poster prizes |
End of the seminar and departure